Article

Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

2020-04-08

Abstract excerpt

<title>Abstract</title> <p>Background: Metastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes. Previous studies have linked chromosomal instability (CIN), which generates aneuploidy following chromosomal missegregation during mitosis, to PC progression. Evidence of CIN...

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Literature Corpus work: 1e349522-bed5-5172-842a-817dcefa2016
DOI: 10.21203/rs.2.21611/v4

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