Article

Plasma sex hormone-binding globulin predicts neurodegeneration and clinical progression in prodromal Alzheimer's disease

2019-12-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Sex hormone-binding globulin (SHBG) in plasma has been found to be significantly elevated in subjects with AD. We aimed to investigate whether plasma SHBG was associated with AD biomarkers and could predict neurodegeneration and clinical progression in prodromal AD.<bold>Methods</bold>: The study tested the cross-sectional relationship between plasma SHBG and CS...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1e13d1d1-1bee-5b9c-8f83-50b75edbf673
DOI: 10.21203/rs.2.18945/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Plasma sex hormone-binding globulin predicts neurodegeneration and clinical progression in prodromal Alzheimer's diseaseDOI 10.21203/rs.2.18945/v1Read

Steroid Hormones in Dementia: A Cross-Diagnostic Molecular Analysis of Blood and Cerebrospinal FluidSemantic proximity Read

Sex Differences in the Relationship of Biomarker Change to Memory Decline in Early Alzheimer’s Disease: an Observational Cohort StudySemantic proximity Read

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.Semantic proximity Read

APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls.Semantic proximity Read

Sex-specific genetic predictors of Alzheimer's disease biomarkers.Semantic proximity Read

APOE4 and Chronic Health Risk Factors are Associated with Sex-Specific Preclinical Alzheimers Disease Neuroimaging BiomarkersSemantic proximity Read

Sex modifies the APOE-related risk of developing Alzheimer disease.Semantic proximity Read

Sex-Specific Metabolic Pathways Were Associated with Alzheimer’s Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery CohortSemantic proximity Read

Causal Relationship between Sex Hormones and Risk of Developing Common Neurodegenerative Diseases: A Mendelian Randomization StudySemantic proximity Read

Distinctive Temporal Trajectories of Alzheimer’s Disease Biomarkers According to Sex and APOE Genotype: Importance of Striatal AmyloidSemantic proximity Read

Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementiaSemantic proximity Read