Article

<i>N</i>-glycans mannosylation controls T-cell development by reprogramming thymocyte commitment, fate and repertoire

2022-02-06

Abstract excerpt

T-cell development is a major physiological process occurring in complex organisms, that ensures the formation of T-cell receptors diverse repertoire, to recognize antigens throughout the life of the organism. The thymus offers a microenvironment for efficient development, where progenitor populations go through maturation steps, which, when not regulated, are associated with disease onset, including autoimmune di...

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Literature Corpus work: 1dfd7cc4-fa6e-5930-a8ae-e8a2f9640764
DOI: 10.1101/2022.02.04.22270265

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