Article
Revisiting the immunopathology of congenital disorders of glycosylation: an updated review.
Frontiers in immunology - 1 Jan 2024
Pascoal Carlota, Francisco Rita, Mexia Patrícia, Pereira Beatriz Luís, Granjo Pedro, Coelho Helena, Barbosa Mariana, Dos Reis Ferreira Vanessa, Videira Paula Alexandra
Abstract excerpt
Glycosylation is a critical post-translational modification that plays a pivotal role in several biological processes, such as the immune response. Alterations in glycosylation can modulate the course of various pathologies, such as the case of congenital disorders of glycosylation (CDG), a group of more than 160 rare and complex genetic diseases. Although the link between glycosylation and immune dysfunction has...
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