Article

Crowd-sourced benchmarking of single-sample tumour subclonal reconstruction

2022-06-15

Abstract excerpt

Tumours are dynamically evolving populations of cells. Subclonal reconstruction algorithms use bulk DNA sequencing data to quantify parameters of tumour evolution, allowing assessment of how cancers initiate, progress and respond to selective pressures. A plethora of subclonal reconstruction algorithms have been created, but their relative performance across the varying biological and technical features of real-wo...

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Literature Corpus work: 1dfc803a-3ee7-593d-a82d-d85f91aa99c7
DOI: 10.1101/2022.06.14.495937

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