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Disruption of a <i>RAC1</i> -centred protein interaction network is associated with Alzheimer’s disease pathology and causes age-dependent neurodegeneration

2019-07-24

Abstract excerpt

The molecular biological mechanisms of Alzheimer’s disease (AD) involve disease-associated cross-talk through many genes and include a loss of normal as well as a gain of abnormal interactions among genes. A protein domain network (PDN) is a collection of physical bindings that occur between protein domains, and the states of the PDNs in patients with AD are likely to be perturbed compared to those in normal healt...

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Literature Corpus work
1dada8d9-e280-5e8b-b28c-c8c3811d3790
DOI
10.1101/713222
Open publication

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Disruption of a <i>RAC1</i> -centred protein interaction network is associated with Alzheimer’s disease pathology and causes age-dependent neurodegenerationDOI 10.1101/713222
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