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Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brains

1 Sept 2010

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a major neurodegenerative disorder leading to amnesia, cognitive impairment and dementia in the elderly. Usually this type of lesions results from dysfunctional protein cooperations in the biological pathways. In addition, AD progression is known to occur in different brain regions with particular features. Thus identification and analysis of crosstalk among dysregulated...

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PMID: 20840725
DOI: 10.1186/1752-0509-4-s2-s11

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