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Machine Learning Reveals Key Glycoprotein Mutations and Rapidly Assigns Lassa Virus Lineages

2024-07-31

Abstract excerpt

Lassa fever, caused by the Lassa virus (LASV), remains a major public health concern in West Africa, causing numerous fatalities annually and several intercontinental cases since its discovery in 1969. Despite ongoing research, no approved vaccines are available, with current efforts focusing on immunotherapy. LASV is divided into distinct lineages that circulate in specific geographic regions, elicit varying immu...

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Literature Corpus work
1da21908-bd80-5f0b-80b5-1c12d721fa75
DOI
10.1101/2024.07.31.605963
Open publication

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Machine Learning Reveals Key Glycoprotein Mutations and Rapidly Assigns Lassa Virus LineagesDOI 10.1101/2024.07.31.605963
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