Article

Engineered ACE2 counteracts vaccine-evading SARS-CoV-2 Omicron variant

2021-12-23

Abstract excerpt

The novel SARS-CoV-2 variant, Omicron (B.1.1.529) contains an unusually high number of mutations (>30) in the spike protein, raising concerns of escape from vaccines, convalescent sera and therapeutic drugs. Here we analyze the alteration of neutralizing titer with Omicron pseudovirus. Sera obtained 3 months after double BNT162b2 vaccination exhibit approximately 18-fold lower neutralization titers against Omicron...

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Literature Corpus work: 1d9e7a74-cf30-5a95-9835-74f16c93369a
DOI: 10.1101/2021.12.22.473804

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