Article

SARS-CoV-2 Omicron variant escapes neutralization by vaccinated and convalescent sera and therapeutic monoclonal antibodies

2021-12-14

Abstract excerpt

The novel SARS-CoV-2 variant, Omicron (B.1.1.529) contains about 30 mutations in the spike protein and the numerous mutations raise the concern of escape from vaccine, convalescent sera and therapeutic drugs. Here we analyze the alteration of their neutralizing titer with Omicron pseudovirus. Sera of 3 months after double BNT162b2 vaccination exhibite ∼27-fold lower neutralization titers against Omicron than D614G...

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Literature Corpus work: 07f4fb59-88c0-544d-a80c-ff24e777699d
DOI: 10.1101/2021.12.13.21267761

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