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Article

Connexin43 in mesenchymal lineage cells regulates body adiposity and energy metabolism in mice

2024-01-07

Abstract excerpt

Connexin43 (Cx43) is the most abundant gap junction protein present in the mesenchymal lineage. In mature adipocytes, Cx43 mediates white adipose tissue (WAT) “beiging” in response to cold exposure and maintains the mitochondrial integrity of brown adipose tissue (BAT). We found that genetic deletion of Gja1 (Cx43 gene) in cells that give rise to chondro-osteogenic and adipogenic precursors driven by the Dermo1/...

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Identifiers and source

Literature Corpus work
1d7f455b-87c8-5622-aed6-9ae4a6a24e5f
DOI
10.1101/2024.01.05.574415
Open publication

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Connexin43 in mesenchymal lineage cells regulates body adiposity and energy metabolism in miceDOI 10.1101/2024.01.05.574415
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