Article

Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss

2024-10-11

Abstract excerpt

<title>Abstract</title> <p>Background: During fertilization, spermatozoa contribute genetic and epigenetic factors such as chromatin packaged with protamines and histones; DNA methylome, micro RNAs etc. Human sperm chromatin retains 5–15% nucleosomes which can play a key role in embryonic development. Recurrent Pregnancy loss (RPL) is a condition mainly attributed to defects in embryo and placenta development. M...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1d2e9dc4-53e2-5df9-b1e0-46f6e05c7bee
DOI: 10.21203/rs.3.rs-4901487/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy lossDOI 10.21203/rs.3.rs-4901487/v1Read

Comprehensive DNA methylation profiling of sperm in male partners of couples with unexplained recurrent pregnancy lossSemantic proximity Read

Insights into the sperm chromatin and implications for male infertility from a protein perspectiveSemantic proximity Read

Sperm chromatin: Evaluation, epigenetic signatures and relevance for embryo development and assisted reproductive technology outcomesSemantic proximity Read

Aberrant protamine content in sperm and consequential implications for infertility treatment.Semantic proximity Read

Altered histone retention and epigenetic modifications in the sperm of infertile menSemantic proximity Read

Essential Role of Histone Replacement and Modifications in Male FertilitySemantic proximity Read

Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertilitySemantic proximity Read

An aberrant protamine ratio is associated with decreased H4ac levels in murine and human spermSemantic proximity Read

Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic PatternSemantic proximity Read

[Role of sperm genetic abnormality in recurrent pregnancy loss: An update].Semantic proximity Read

Dynamic alterations in the paternal epigenetic landscape following fertilizationSemantic proximity Read

Histone retention, protein carbonylation, and lipid peroxidation in spermatozoa: Possible role in recurrent pregnancy lossSemantic proximity Read