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Loratadine decreases methicillin-resistant <i>Staphylococcus aureus</i> virulence through global hemolysin regulators <i>vraSR</i> and <i>agr</i>

2025-06-05

Abstract excerpt

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen that relies on expression of a wide range of virulence factors. Hemolysins are a diverse collection of cytolytic toxins that promote virulence by being excreted and lysing host blood cells. We previously reported on novel anti-virulence compounds that modulate hemolysis in vitro, including a brominated carbazole (compound 8) and the active...

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Literature Corpus work
1d2bc401-12b7-59fd-b010-28c1fdb59fec
DOI
10.1101/2025.06.05.657702
Open publication

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Loratadine decreases methicillin-resistant <i>Staphylococcus aureus</i> virulence through global hemolysin regulators <i>vraSR</i> and <i>agr</i>DOI 10.1101/2025.06.05.657702
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