Article
Staphylococcus aureus Strain Newman D2C Contains Mutations in Major Regulatory Pathways That Cripple Its Pathogenesis.
Journal of bacteriology - 15 Dec 2017
Sause William E, Copin Richard, O'Malley Aidan, Chan Rita, Morrow Brian J, Buckley Peter T, Fernandez Jeffrey, Lynch A Simon, Shopsin Bo, Torres Victor J
Abstract excerpt
Staphylococcus aureus is a major human pathogen that imposes a great burden on the health care system. In the development of antistaphylococcal modalities intended to reduce the burden of staphylococcal disease, it is imperative to select appropriate models of S. aureus strains when assessing the efficacy of novel agents. Here, using whole-genome sequencing, we reveal that the commonly used strain Newman D2C from...
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