Article
Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes.
Nucleic acids research - 22 Feb 2022
Pathak Ankit K, Mishra Gyan Prakash, Uppili Bharathram, Walia Safal, Fatihi Saman, Abbas Tahseen, Banu Sofia, Ghosh Arup, Kanampalliwar Amol, Jha Atimukta, Fatma Sana, Aggarwal Shifu, Dhar Mahesh Shanker, Marwal Robin, Radhakrishnan Venkatraman Srinivasan, Ponnusamy Kalaiarasan, Kabra Sandhya, Rakshit Partha, Bhoyar Rahul C, Jain Abhinav, Divakar Mohit Kumar, Imran Mohamed, Faruq Mohammed, Sowpati Divya Tej, Thukral Lipi, Raghav Sunil K, Mukerji Mitali
Abstract excerpt
During the course of the COVID-19 pandemic, large-scale genome sequencing of SARS-CoV-2 has been useful in tracking its spread and in identifying variants of concern (VOC). Viral and host factors could contribute to variability within a host that can be captured in next-generation sequencing reads as intra-host single nucleotide variations (iSNVs). Analysing 1347 samples collected till June 2020, we recorded 16...
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