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Single-Cell RNA Sequencing Combined with Single-Cell Genome-Wide Association Study Identifies SF3B4 as a hub Gene in Hepatocellular Carcinoma Progression

2025-12-05

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<title>Abstract</title> <p> <bold>Objective</bold> : High heterogeneity and poor therapeutic response are major challenges in hepatocellular carcinoma (HCC). This study aimed to identify core hepatocyte subsets and key genes driving HCC progression via a multi-omics approach to inform precise diagnosis and treatment. <bold>Methods</bold> : We analyzed public data from GEO (GSE282701), TCGA-LIHC, and IEU-Open-...

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Literature Corpus work
6a6b81cd-abfa-5102-87d4-3460f4a4f1f2
DOI
10.21203/rs.3.rs-8020835/v1
Open publication

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Single-Cell RNA Sequencing Combined with Single-Cell Genome-Wide Association Study Identifies SF3B4 as a hub Gene in Hepatocellular Carcinoma ProgressionDOI 10.21203/rs.3.rs-8020835/v1
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