Article

Single-Cell Transcriptome Analysis Identifies Novel Biomarkers Involved in Major Liver Cancer Subtypes

2022-02-04

Abstract excerpt

Liver cancers including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are leading cause of death worldwide. Single-cell transcriptomics studies have vast potential in advancing our understanding of cancers by defining the cellular composition of different solid tumor types. We peformed an integrated analysis using single-cell RNA sequencing (scRNA-seq) data from cancerous and healthy liv...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: df7ed70f-f276-5134-85e3-a2bd71fb0385
DOI: 10.1101/2022.02.01.478756

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-Cell Transcriptome Analysis Identifies Novel Biomarkers Involved in Major Liver Cancer SubtypesDOI 10.1101/2022.02.01.478756Read

Understanding the heterogeneity in liver hepatocellular carcinoma with a special focus on malignant cell through single-cell analysisSemantic proximity Read

Single-cell Transcriptomic Architecture Unraveling the Complexity of Tumor Heterogeneity in Distal CholangiocarcinomaSemantic proximity Read

A Human Liver Cell Atlas: Revealing Cell Type Heterogeneity and Adult Liver Progenitors by Single-Cell RNA-sequencingSemantic proximity Read

Multimodal single-cell network analysis uncovers BSG/CD147 as an early biomarker and signaling hub in hepatocellular carcinomaSemantic proximity Read

Single-cell and spatial architecture of primary liver cancerSemantic proximity Read

Integration of single-cell sequencing and drug sensitivity profiling reveals an 11-gene prognostic model for liver cancer.Semantic proximity Read

Single-Cell Transcriptomic Analysis Reveals Two Molecularly and Clinically Distinct Subtypes of Intrahepatic CholangiocarcinomaSemantic proximity Read

Integrated single-cell transcriptomic atlas of human gastric and colorectal tissues across diverse phenotypes.Semantic proximity Read

Somatic mutation landscape reveals differential variability of cell-of-origin for primary liver cancerSemantic proximity Read

Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancerSemantic proximity Read

Integrated analysis of single-cell transcriptome of liver cancer and cirrhosis reveals cell lineage similarity and prognostic-associated subpopulationsSemantic proximity Read

CancerSCEM: a database of single-cell expression map across various human cancersSemantic proximity Read