Article

Global Cancer Transcriptome Quantifies Repeat Element Polarization Between Immunotherapy Responsive and T cell Suppressive Classes

2017-06-04

Abstract excerpt

<h4>Summary</h4> Growing evidence indicates that innate immune pathway activation is critical for responses to immunotherapy and overall cancer prognosis. It has been posited that innate immunity in the tumor microenvironment can be driven by derepression of endogenous repetitive element RNA. The ability to characterize these species can potentially provide novel predictive biomarkers for tumor immune responses a...

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Literature Corpus work: 1c9cfde6-58fa-503d-8fb3-33ab07d1108a
DOI: 10.1101/145946

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