Article

Functional transcriptional signatures for tumor-type-agnostic phenotype prediction

2023-04-13

Abstract excerpt

Cancer transcriptional patterns exhibit both shared and unique features across diverse cancer types, but whether these patterns are sufficient to characterize the full breadth of tumor phenotype heterogeneity remains an open question. We hypothesized that cancer transcriptional diversity mirrors patterns in normal tissues optimized for distinct functional tasks. Starting with normal tissue transcriptomic profiles,...

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Literature Corpus work: 1c534fd2-1c09-5b5e-98f3-e1b16ff6f099
DOI: 10.1101/2023.04.12.536595

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