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Transcriptomic subtyping of gastrointestinal malignancies

16 Jul 2024

Abstract excerpt

Gastrointestinal (GI) cancers are highly heterogeneous at multiple levels. Tumor heterogeneity can be captured by molecular profiling, such as genetic, epigenetic, proteomic, and transcriptomic classification. Transcriptomic subtyping has the advantage of combining genetic and epigenetic information, cancer cell-intrinsic properties, and the tumor microenvironment (TME). Unsupervised transcriptomic subtyping...

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PMID: 39019673
DOI: 10.1016/j.trecan.2024.06.007

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