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Article

Generalizable transcriptome-based tumor malignant level evaluation and molecular subtyping towards precision oncology.

Journal of translational medicine - 28 May 2024

Hu Dingxue, Zhang Ziteng, Liu Xiaoyi, Wu Youchun, An Yunyun, Wang Wanqiu, Yang Mengqi, Pan Yuqi, Qiao Kun, Du Changzheng, Zhao Yu, Li Yan, Bao Jianqiang, Qin Tao, Pan Yue, Xia Zhaohua, Zhao Xin, Sun Kun

Abstract excerpt

In cancer treatment, therapeutic strategies that integrate tumor-specific characteristics (i.e., precision oncology) are widely implemented to provide clinical benefits for cancer patients. Here, through in-depth integration of tumor transcriptome and patients' prognoses across cancers, we investigated dysregulated and prognosis-associated genes and catalogued such important genes in a cancer type-dependent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38807223
DOI: 10.1186/s12967-024-05326-0
PMCID: PMC11134716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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