Article

UBA52 attunes VDAC1-mediated mitochondrial dysfunction and dopaminergic neuronal death

2022-09-23

Abstract excerpt

Mitochondrial homeostasis regulates energy metabolism, calcium buffering, cell function and apoptosis. The present study has been conducted to investigate the implications of ubiquitin-encoding gene UBA52 in mitochondrial physiology. Transient expression of Myc-UBA52 in neurons significantly inhibited the rotenone-induced increase in reactive oxygen species generation, nitrite level and depleted glutathione level....

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Literature Corpus work: 1be1dbce-b4d6-59a7-a3af-88bf1ebc7cdc
DOI: 10.1101/2022.09.22.508987

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