Article

UBA52 is crucial in HSP90 ubiquitylation and neurodegenerative signaling during early phase of Parkinson’s disease

2022-08-17

Abstract excerpt

Protein aggregation is one of the major pathological events in age-related Parkinson’s disease (PD) pathology, predominantly regulated by the ubiquitin-proteasome system (UPS). UPS essentially requires core component ubiquitin however, its role in PD pathology is obscure. This study aimed to investigate the role of ubiquitin encoding genes in the early phase of PD pathology. Wild-type human Myc-α-synuclein transfe...

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Literature Corpus work: 8feaba32-d942-502b-af90-fce260022c8b
DOI: 10.1101/2022.08.17.504224

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