Article

MicroRNA-21-3p regulation of NOX4 and VEGFA contributes to hemorrhage in cerebral cavernous malformations

2025-10-14

Abstract excerpt

<h4>Objective</h4> MicroRNAs regulate the brain vascular integrity and are involved in the lesion development of cerebral cavernous malformations (CCM). This study examines the role of microRNA-21-3p in CCM-related cerebral hemorrhage and its underlying mechanisms. <h4>Methods</h4> The expression of miRNA-21-3p and its target genes of NADPH oxidase 4 (NOX4) and vascular endothelial growth factor A (VEGFA) in bra...

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Literature Corpus work: 1bdb2bd7-d1c5-5fc8-a7dd-d2ec0e5088db
DOI: 10.1101/2025.10.13.681886

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