Article

G-quadruplex profiling in complex tissues using single-cell CUT&Tag

2025-04-05

Abstract excerpt

G-quadruplexes (G4) are non-canonical DNA structures that gained increasing attention for their potential roles in gene regulation, with implications in neurodegenerative diseases and cancer. Despite their biological significance, G4 structures have not been studied systematically across tissues and cell types. In this study, we employ G4 single-cell CUT&Tag (G4 scCUT&Tag) to characterize G4 landscapes in postnata...

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Literature Corpus work: 1bbfd85d-de8f-57c8-92eb-67ce89af1320
DOI: 10.1101/2025.04.03.647101

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