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Article

Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling.

PloS one - 1 Jan 2014

Erkosar Berra, Erkosar Combe Berra, Defaye Arnaud, Bozonnet Noémie, Puthier Denis, Royet Julien, Leulier François

Abstract excerpt

Most metazoans engage in mutualistic interactions with their intestinal microbiota. Despite recent progress the molecular mechanisms through which microbiota exerts its beneficial influences on host physiology are still largely uncharacterized. Here we use axenic Drosophila melanogaster adults associated with a standardized microbiota composed of a defined set of commensal bacterial strains to study the impact of...

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PMID: 24733183
DOI: 10.1371/journal.pone.0094729
PMCID: PMC3986221

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