Article

Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohnʼs disease

2008-11-20

Abstract excerpt

Large interindividual variation in the composition of the intestinal microbiota between unrelated individuals has made it challenging to identify specific aspects of dysbiosis that lead to Crohn's disease (CD). To reduce variations in exposure during establishment of the gut flora and the influence of genotype, we studied the mucosa-associated microbiota of monozygotic twin pairs that were discordant (n = 6) or co...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1b7a5fa2-8d07-590b-bffd-ffaa9b59874b
DOI: 10.1002/ibd.20783

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohnʼs diseaseDOI 10.1002/ibd.20783Read

A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes.Semantic proximity Read

Molecular analysis of the gut microbiota of identical twins with Crohn's diseaseSemantic proximity Read

The gut microbiota of siblings offers insights into microbial pathogenesis of inflammatory bowel disease.Semantic proximity Read

Distinct Microbiotas are Associated with Ileum-Restricted and Colon-Involving Crohnʼs DiseaseSemantic proximity Read

Siblings of patients with Crohn's disease exhibit a biologically relevant dysbiosis in mucosal microbial metacommunities.Semantic proximity Read

Microbiota of De-Novo Pediatric IBD: Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative ColitisSemantic proximity Read

Bacteria in the pathogenesis of inflammatory bowel diseaseSemantic proximity Read

Establishing a novel inflammatory bowel disease prediction model based on gene markers identified from single nucleotide variants of the intestinal microbiotaSemantic proximity Read

Inflammatory potential of gut microbiota from monozygotic twin pair discordant for ulcerative colitisSemantic proximity Read

Metagenomic Analysis of Crohnʼs Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and BiomarkersSemantic proximity Read

Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition.Semantic proximity Read

Healthy Cotwins Share Gut Microbiome Signatures With Their Inflammatory Bowel Disease Twins and Unrelated Patients.Semantic proximity Read