Article
A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes.
Gastroenterology - 1 Dec 2010
Willing Ben P, Dicksved Johan, Halfvarson Jonas, Andersson Anders F, Lucio Marianna, Zheng Zongli, Järnerot Gunnar, Tysk Curt, Jansson Janet K, Engstrand Lars
Abstract excerpt
BACKGROUND & AIMS: The composition of the gastrointestinal microbiota is thought to have an important role in the etiology of inflammatory bowel diseases (IBDs) such as Crohn's disease (CD) and ulcerative colitis (UC). Interindividual variation and an inability to detect less abundant bacteria have made it difficult to correlate specific bacteria with disease. METHODS: We used 454 pyrotag sequencing to determine...
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