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Article

The gut microbiota of siblings offers insights into microbial pathogenesis of inflammatory bowel disease.

Gut microbes - 4 Jul 2017

Hedin Charlotte R, van der Gast Christopher J, Stagg Andrew J, Lindsay James O, Whelan Kevin

Abstract excerpt

Siblings of patients with Crohn's disease (CD) have elevated risk of developing CD and display aspects of disease phenotype, including faecal dysbiosis. In our recent article we have used 16S rRNA gene targeted high-throughput sequencing to comprehensively characterize the mucosal microbiota in healthy siblings of CD patients, and determine the influence of genotypic and phenotypic factors on the gut microbiota...

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Bacteria
Dysbiosis
Gastrointestinal Microbiome
Genotype
Gut microbiota and health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Inflammatory Bowel Diseases

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Open in PubMed Open full text

Identifiers

PMID: 28112583
DOI: 10.1080/19490976.2017.1284733
PMCID: PMC5570433

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