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Article

Molecular analysis of the gut microbiota of identical twins with Crohn's disease

10 Apr 2008

Abstract excerpt

Increasing evidence suggests that a combination of host genetics and the composition of the gut microbiota are important for development of Crohn's disease (CD). Our aim was to study identical twins with CD to determine microbial factors independent of host genetics. Fecal samples were studied from 10 monozygotic twin pairs with CD (discordant n=6 and concordant n=4) and 8 healthy twin pairs. DNA was extracted,...

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PMID: 18401439
DOI: 10.1038/ismej.2008.37

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