Article

Enzymology of gentamicin biosynthesis

2018-01-01

Abstract excerpt

Gentamicin C complex is a mixture of five structurally similar aminoglycoside antibiotics, gentamicins C1, C1a, C2, C2a, and C2b, produced by the actinomycete bacterium Micromonospora echinospora. It is established in clinical use and despite significant toxicity remains valuable to treat severe Gram-negative bacterial infections. There is a pressing need to develop novel versions of such antibiotics to combat the...

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Literature Corpus work: 1b7343ad-c772-51ea-b393-52db7bd84148
DOI: 10.17863/cam.25238

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