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Validation and Characterization of a Novel Blood-Brain Barrier Platform for Investigating Traumatic Brain Injury

2022-11-22

Abstract excerpt

The Blood-Brain Barrier (BBB) is a highly-selective physiologic barrier responsible for maintaining cerebral homeostasis. Innovative in vitro models of the BBB are needed to provide useful insights into BBB function with CNS disorders like TBI. Current models either lack fluidic shear stress, or neglect hemodynamic parameters important in recapitulating the human in vivo BBB phenotype. To address these limitations...

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Literature Corpus work
1b69820c-1f2a-58c2-b82f-2a872b3bf6c9
DOI
10.21203/rs.3.rs-2256629/v1
Open publication

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Validation and Characterization of a Novel Blood-Brain Barrier Platform for Investigating Traumatic Brain InjuryDOI 10.21203/rs.3.rs-2256629/v1
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