Article

Real-Time, Direct Classification of Nanopore Signals with SquiggleNet

2021-01-17

Abstract excerpt

Oxford Nanopore sequencers provide results in real time as DNA passes through a nanopore and can eject a molecule after it has been partly sequenced. However, the computational challenge of deciding whether to keep or reject a molecule in real time has limited the application of this capability. We present SquiggleNet, the first deep learning model that can classify nanopore reads directly from their electrical si...

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Identifiers and source

Literature Corpus work: e553eb61-c5ac-5326-a5c4-1585fd4231ef
DOI: 10.1101/2021.01.15.426907

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