Article

Structural insights into the inactive state of the adhesion GPCR ADGRV1

2026-03-07

Abstract excerpt

Adhesion G protein-coupled receptors (aGPCRs) are involved in numerous physiological processes, including cell-cell and cell-matrix interactions, and are associated with several human diseases. ADGRV1 is a member of the aGPCR family and plays a significant role in the sensorineural systems. Mutations of ADGRV1 are linked to the Usher syndrome, a genetic disorder causing deafness and blindness in human. However, th...

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Literature Corpus work: 1afbb828-17ed-5351-950a-3ae16cde9ced
DOI: 10.64898/2026.03.05.709805

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