Article

Recurrently Mutated Genes Differ between Leptomeningeal and Solid Lung Cancer Brain Metastases

2017-11-20

Abstract excerpt

<h4>Purpose</h4> Brain metastases from non-small cell lung cancer (NSCLC) engraft and grow either within the brain (solid) or diffusely on its surface (leptomeningeal disease; LMD). Routine clinical diagnostics have low sensitivity and provide no information about the underlying mutations. A recurrent mutation analysis of LMD and a comparison between solid and LMD NSCLC brain metastases have yet to be explored. <...

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Literature Corpus work: 1a854f5e-cf1c-5bf7-921c-26baa5d8dc30
DOI: 10.1101/222349

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