Article

Molecular design, optimization and genomic integration of chimeric B cell receptors in murine B cells

2019-01-17

Abstract excerpt

Immune cell therapies based on the integration of synthetic antigen receptors provide a powerful strategy for the treatment of diverse diseases, most notably retargeting T cells engineered to express chimeric antigen receptors (CAR) for cancer therapy. In addition to T lymphocytes, B lymphocytes may also represent valuable immune cells that can be engineered for therapeutic purposes such as protein replacement the...

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Literature Corpus work: 1a7a8fd6-06fc-5ba1-b7fb-b86de9454332
DOI: 10.1101/516369

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