Article
Precise Structural Analysis of Neutral Glycans Using Aerolysin Mutant T240R Nanopore.
ACS nano - 14 May 2024
Lu Wenqi, Zhao Xinjia, Li Minmin, Li Yuting, Zhang Chen, Xiong Yuting, Li Jiaqi, Zhou Han, Ye Xianlong, Li Xiaonong, Wang Jing, Liang Xinmiao, Qing Guangyan
Abstract excerpt
Glycans play vital roles in nearly all life processes of multicellular organisms, and understanding these activities is inseparable from elucidating the biological significance of glycans. However, glycan research has lagged behind that of DNA and protein due to the challenges posed by structural heterogeneity and isomerism (i.e., structures with equal molecular weights) the lack of high-efficiency structural...
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