Article

Prognostic value of circulating H3K27Me3-nucleosomes in newly diagnosed lung cancer patients

2026-06-02

Abstract excerpt

<title>Abstract</title> <p>Lung cancer remains a leading cause of cancer-related mortality, with heterogeneous outcomes, underscoring the need for robust prognostic biomarkers. Circulating tumor DNA (ctDNA) enables detection of actionable mutations and may provide prognostic information; however, many patients lack detectable alterations, limiting its utility for molecular-based risk stratification. We analyzed p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1a0ae7d1-f8dd-5392-b215-c59858c64aea
DOI: 10.21203/rs.3.rs-9880337/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Prognostic value of circulating H3K27Me3-nucleosomes in newly diagnosed lung cancer patientsDOI 10.21203/rs.3.rs-9880337/v1Read

Circulating H3K27 Methylated Nucleosome plasma concentration: a synergistic information with ctDNA Molecular ProfilingSemantic proximity Read

Chromatin- and nucleosome-associated features in liquid biopsy: implications for cancer biomarker discoverySemantic proximity Read

Cell‐free chromatin immunoprecipitation can determine tumor gene expression in lung cancer patientsSemantic proximity Read

Beyond mutations: epigenetic and fragmentomic landscapes of cfDNA in lung cancer.Semantic proximity Read

Plasma Exosomal DNA Methylation Profiles and Therapeutic Response in Non-Small Cell Lung CancerSemantic proximity Read

Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancerSemantic proximity Read

Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypesSemantic proximity Read

Nucleosome reorganisation in breast cancer tissuesSemantic proximity Read

Direct analysis of transcription factor protected cfDNA in plasma by ChIP-seq: Measurement of altered CTCF binding in cancer is a novel biomarker for liquid biopsySemantic proximity Read

Simulating cell-free chromatin using preclinical models for cancer-specific biomarker discoverySemantic proximity Read

5-hydroxymethylcytosine Profilings in Circulating Cell-free DNA as diagnostic biomarkers for DLBCLSemantic proximity Read

Association between the nucleosome footprint of plasma DNA and neoadjuvant chemotherapy response for breast cancerSemantic proximity Read