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Article

Availability of abundant thiamine determines efficiency of thermogenic activation in human neck area derived adipocytes

2022-05-05

Abstract excerpt

Brown/beige adipocytes express uncoupling protein-1 (UCP1) that enables them to dissipate energy as heat. Systematic activation of this process can alleviate obesity. Human brown adipose tissues are interspersed in distinct anatomical regions including deep neck. We found that UCP1 enriched adipocytes differentiated from precursors of this depot highly expressed ThTr2 transporter of thiamine and consumed thiamine...

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Identifiers and source

Literature Corpus work
19f98507-b62d-54cb-947b-345081e4e820
DOI
10.1101/2022.05.05.490662
Open publication

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Availability of abundant thiamine determines efficiency of thermogenic activation in human neck area derived adipocytesDOI 10.1101/2022.05.05.490662
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