Article

Extracellular thiamine concentration influences thermogenic competency of differentiating neck area-derived human adipocytes

2023-04-13

Abstract excerpt

Brown adipose tissue (BAT) dissipates energy in the form of heat majorly via the mitochondrial uncoupling protein 1 (UCP1). The activation of BAT, which is enriched in the neck area and contains brown and beige adipocytes in humans, was considered as a potential therapeutic target to treat obesity. Therefore, finding novel agents that can stimulate the differentiation and recruitment of brown or beige thermogenic...

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Literature Corpus work: 011be1e6-3a62-5e6f-9198-747a20371627
DOI: 10.1101/2023.04.13.536432

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