Article

An immunodominance hierarchy exists in CD8 <sup>+</sup> T cell responses to HLA-A*02:01-restricted epitopes identified from the non-structural polyprotein 1a of SARS-CoV-2

2020-09-19

Abstract excerpt

COVID-19 vaccines are being rapidly developed and human trials are underway. Almost all of these vaccines have been designed to induce antibodies targeting spike protein of SARS-CoV-2 in expectation of neutralizing activities. However, non-neutralizing antibodies are at risk of causing antibody-dependent enhancement. Further, the longevity of SARS-CoV-2-specific antibodies is very short. Therefore, in addition to...

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Literature Corpus work: 19f8a389-ad2f-5566-b024-804d4c3aa28d
DOI: 10.1101/2020.09.18.304493

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