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Angiotensin II Type 1 Receptor Blockade Inhibits Gastric Cancer Metastasis Through Tight Junction Restoration

2026-01-09

Abstract excerpt

<h4>ABSTRACT</h4> Cell-Cell adhesion maintained by tight junctions (TJs) is essential for epithelial integrity; loss of TJs correlates with poor prognosis, metastasis, and adverse clinical outcome in gastric cancer (GC). Restoring TJ integrity is therefore considered a promising therapeutic strategy in GC. The study identifies the stomach renin angiotensin system (stRAS) as a crucial regulator of TJ function in G...

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Literature Corpus work
19cbf4fd-8150-59bf-ba0e-aa843fb0dcc2
DOI
10.64898/2026.01.08.698396
Open publication

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