Article

Targeted mRNA demethylation in Arabidopsis using the human ALKBH5 catalytic domain

2022-06-30

Abstract excerpt

N6-methyladenosine (m6A) is an important epigenetic modification involved in RNA stability and translation regulation. Manipulating the expression of RNA m6A methyltransferases or demethylases makes it difficult to study the effect of specific RNA methylation. Recently, m6A editor was reported to manipulate RNA methylation in a locus-specific manner in human cells, but it remains unclear whether this tool can be u...

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Literature Corpus work: 19b172b3-233e-5f0e-bc07-d214f3b2e378
DOI: 10.21203/rs.3.rs-1733252/v1

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