Article

MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis

2019-03-03

Abstract excerpt

<h4>ABSTRACT</h4> Melanoma with rapid progression towards metastasis becomes the deadliest form of skin cancer. However, the mechanism of melanoma growth and metastasis is still unclear. Here, we found that miRNA-138 was low expression and hypoxia-inducible factor 1α (HIF1α) was high expression in the patient’s melanoma tissue, and they had a significant negative correlation (r = -0.937, P < 0.001). Patients wit...

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Literature Corpus work: 19950945-aaa2-5f14-a737-e4445605b818
DOI: 10.1101/566224

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