Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Viral and cellular translation during SARS‐CoV‐2 infection

16 Apr 2022

Abstract excerpt

SARS-CoV-2 is a betacoronavirus that emerged in China in December 2019 and which is the causative agent of the Covid-19 pandemic. This enveloped virus contains a large positive-sense single-stranded RNA genome. In this review, we summarize the current knowledge on the molecular mechanisms for the translation of both viral transcripts and cellular messenger RNAs. Non-structural proteins are encoded by the genomic...

Source

Identifiers

PMID: 35429230
DOI: 10.1002/2211-5463.13413

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Viral and cellular translation during SARS‐CoV‐2 infectionPMID 35429230Read ↗

The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translationSemantic proximity Read ↗

Coronavirus takeover of host cell translation and intracellular antiviral response: a molecular perspectiveSemantic proximity Read ↗

Translational Control of COVID-19 and Its Therapeutic ImplicationSemantic proximity Read ↗

Parsing the role of NSP1 in SARS-CoV-2 infectionSemantic proximity Read ↗

I(nsp1)ecting SARS-CoV-2–ribosome interactionsSemantic proximity Read ↗

Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNASemantic proximity Read ↗

Cap-independent translation and a precisely located RNA sequence enable SARS-CoV-2 to control host translation and escape anti-viral responseSemantic proximity Read ↗

The N-Terminal and Central Domains of CoV-2 nsp1 Play Key Functional Roles in Suppression of Cellular Gene Expression and Preservation of Viral Gene ExpressionSemantic proximity Read ↗

Targeting stem-loop 1 of the SARS-CoV-2 5′ UTR to suppress viral translation and Nsp1 evasionSemantic proximity Read ↗

SARS-CoV-2 utilizes a multipronged strategy to suppress host protein synthesisSemantic proximity Read ↗

Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug designSemantic proximity Read ↗

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.