Back to search

Article

Comprehensive IsomiR sequencing profile of human pancreatic islets and EndoC-βH1 beta-cells

2023-11-08

Abstract excerpt

<h4>Aims/Hypothesis</h4> MiRNAs play a crucial role in regulating the islet transcriptome, influencing beta cell functions and pathways. Emerging evidence suggests that during biogenesis a single miRNA locus can generate various sequences, known as isomiRNAs (isomiRs). However, a comprehensive profiling analysis of isomiRs in human pancreatic islets and beta cells is still lacking. This study aims to unveil the i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
19804d3e-d467-5cd8-a86e-6fc48427c786
DOI
10.1101/2023.11.08.566223
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Comprehensive IsomiR sequencing profile of human pancreatic islets and EndoC-βH1 beta-cellsDOI 10.1101/2023.11.08.566223
Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cellsSemantic proximity
Beta Cell 5′-Shifted isomiRs Are Candidate Regulatory Hubs in Type 2 DiabetesSemantic proximity
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.Semantic proximity
PanCircBase: An online resource for the exploration of circular RNAs in pancreatic isletsSemantic proximity
Lessons from single-cell RNA sequencing of human isletsSemantic proximity
Title: β Cell microRNAs Function as Molecular Hubs of Type 1 Diabetes Pathogenesis and as Biomarkers of Diabetes RiskSemantic proximity
High-throughput analysis of ANRIL circRNA isoforms in human pancreatic isletsSemantic proximity
Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysisSemantic proximity
Role of non‐coding RNA s in pancreatic beta‐cell development and physiologySemantic proximity
MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic IsletsSemantic proximity
Emerging roles of non‐coding <scp>RNAs</scp> in pancreatic β‐cell function and dysfunctionSemantic proximity
HNF1α maintains pancreatic α and β cell functions in primary human isletsSemantic proximity
Select a neighboring publication to make it the new centre.