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Article

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.

PloS one - 1 Jan 2013

van de Bunt Martijn, Gaulton Kyle J, Parts Leopold, Moran Ignasi, Johnson Paul R, Lindgren Cecilia M, Ferrer Jorge, Gloyn Anna L, McCarthy Mark I

Abstract excerpt

Recent advances in the understanding of the genetics of type 2 diabetes (T2D) susceptibility have focused attention on the regulation of transcriptional activity within the pancreatic beta-cell. MicroRNAs (miRNAs) represent an important component of regulatory control, and have proven roles in the development of human disease and control of glucose homeostasis. We set out to establish the miRNA profile of human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23372846
DOI: 10.1371/journal.pone.0055272
PMCID: PMC3555946

Genes

KCNK16
NOTCH2
WFS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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