Article
Emerging roles of non‐coding <scp>RNAs</scp> in pancreatic β‐cell function and dysfunction
28 Aug 2012
Abstract excerpt
Pancreatic β-cells play a central role in glucose homeostasis by tightly regulating insulin release according to the organism's demand. Impairment of β-cell function due to hostile environment, such as hyperglycaemia and hyperlipidaemia, or due to autoimmune destruction of β-cells, results in diabetes onset. Both environmental factors and genetic predisposition are known to be involved in the development of the...
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