Article

Synthesize Heterogeneous Biological Knowledge via Representation Learning for Alzheimer’s Disease Drug Repurposing

2021-12-05

Abstract excerpt

<h4>Summary</h4> Developing drugs for treating Alzheimer’s disease (AD) has been extremely challenging and costly due to limited knowledge on underlying biological mechanisms and therapeutic targets. Repurposing drugs or their combination has shown potential in accelerating drug development due to the reduced drug toxicity while targeting multiple pathologies. To address the challenge in AD drug development, we de...

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Literature Corpus work: 197dcd07-8c63-54f8-a06a-da58c009a9fc
DOI: 10.1101/2021.12.03.21267235

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