Article

Integrating explainable AI with multiomics systems biology and EHR data mining for personalized drug repurposing in Alzheimer’s disease

2025-03-28

Abstract excerpt

Alzheimer’s disease (AD) is characterized by region- and patient-specific molecular heterogeneity, which hinders therapeutic design. In this study, we introduce PRISM-ML (PRecision-medicine using Interpretable Systems and Multiomics with Machine Learning), an open-source integrated analysis pipeline that combines interpretable machine learning with systems biology and electronic health record (EHR) data mining to...

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Literature Corpus work: 3abf8061-cec1-5904-b9c5-c812cbd1c2a2
DOI: 10.1101/2025.03.24.644676

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